Joint Research Funding Announcement


Joint Research Funding Announcement: 

The Mechanisms Behind Hypermobile Ehlers-Danlos Syndrome, Mast Cell Activation Syndrome, and Dysautonomia.

Over the last decade, community members of these organizations have reported symptoms and flares that are associated with the three conditions, Hypermobile Ehlers-Danlos syndrome (hEDS), mast cell activation syndrome (MCAS), and Dysautonomia in some individuals. While several mechanisms linking these conditions have been proposed, clear pathophysiological research confirming these mechanisms is lacking. The impact on quality of life and ability to engage in daily activities is severely impacted in each of the three conditions, and these impacts are magnified in those who have two or all three of the conditions. Therefore, The Ehlers-Danlos Society, and The Mast Cell Disease Society are requesting funding proposals for this first joint grant opportunity.

The priority for The Mechanisms Behind Hypermobile Ehlers-Danlos Syndrome, Mast Cell Activation Syndrome, and Dysautonomia is to fund clinically relevant studies that encompass aspects of all three disorders. Applications will be considered if all three disorders are included in a meaningful investigation elucidating biological mechanisms underlying these diseases in specific, well-defined patient populations. Investigators should identify the gap in knowledge to be addressed, and the topic(s) of investigation must integrate information derived from those with all three disorders and allow conclusions to be drawn that will benefit people in all three communities. Patient inclusion criteria must be well delineated, and the study design must be clearly presented. The successful applicant will have an established expertise in their field(s) and include expert collaborators as needed. Collaborative, multidisciplinary teams are encouraged to apply.

To learn more please click here and to apply click here.