2018 TMS Research Grant Awards

The Mastocytosis Society, Inc. (TMS) has awarded three research grants totaling $170,000 to support research in Pediatric Mastocytosis.

The Mastocytosis Society, Inc. (TMS) has awarded three research grants totaling $170,000 to support research in Pediatric Mastocytosis, including Related Disorders of Pediatric Mast Cell Activation. These grants were made possible by generous donations from the Catalano Family through Wyatt’s Warriors, and from Karen and Jim Houghton.

TMS congratulates our 2018 Research Grant recipients!

This grant award was funded by TMS, thanks to a generous donation from the Catalano Family through Wyatt’s Warriors.

Award amount: $50,000

Award recipient:

Anupama Ravi, MD

Mayo Clinic Program for the Study of Mast Cell and Eosinophil Disorders

Division of Pediatric Allergy and Immunology

Mayo Clinic, Rochester, MN

Co-investigators:

Joseph Butterfield, MD

Jeffrey Meeusen, PhD

Leslie Donato, PhD

Angela Mattke, MD

Mayo Clinic, Rochester, MN

Title:   Excretion of Mast Cell Mediators in Pediatric Mastocytosis and Mast Cell Activation Syndrome (MCAS)

These researchers will conduct a study to determine the range levels of urinary mast cell mediators in patients with pediatric mastocytosis, MCAS, anaphylaxis and urticaria/angioedema, as well as in healthy children (controls).

This grant award was funded by TMS, thanks to a generous donation from Karen and Jim Houghton.

Award amount: $60,000

Award recipient:

Olivier Hermine, MD, PhD, and Leila Maouche Chrétien, PhD

Necker Children’s Hospital/Imagine Institute, National Reference Center of Mastocytosis, Paris, France

Title:   Translational Studies on Pediatric Mastocytosis for Identification of New Pathways of Transformation and of New Potentially Effective Treatment of Both Pediatric and Adult Mastocytosis

These researchers will evaluate a cell signaling pathway that is newly associated with mastocytosis, with a goal to study a novel potential therapeutic target.

This grant award was funded by TMS, thanks to a generous donation from Karen and Jim Houghton.

Award amount: $60,000

Award recipient:

Matthew Giannetti, MD

Co-investigator:  Mariana Castells, MD, PhD

Department of Rheumatology, Allergy, and Immunology

Center of Excellence for Mastocytosis

Brigham and Women’s Hospital

Boston, MA

Title:   Identification of Novel Pathways in the Transcriptome of Human Mast Cells from Children and Adults with Cutaneous Mastocytosis

These researchers will explore gene expression in skin mast cells, comparing data from skin biopsy samples from children and adults with cutaneous mastocytosis and from patients without the disease. The researchers hope to identify novel pathways that may play a role in mastocytosis.